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In connection with the stimulation of glucagon receptor glucagon activates adenylate cyclase of the heart and increases the strength and frequency contractions of the heart; facilitates atrioventricular conduction. Biguanides. Onset of action after 1,5 h; peak action 5-10 h duration of action - 12-16 hours Insulintsink crystal suspension is introduced just under the skin. Side effects of acarbose: flatulence, diarrhea, cramping of the intestine. Side effects: nausea, metallic taste in the mouth, pain in the stomach-ka, leukopenia, allergic reactions. Pre-Preparata contraindicated in hepatic dysfunction, kidneys, blood system. With a lack of mineralocorticoid (eg, Addison's disease) increase ourselves to the allocation of water and sodium by the kidneys that leads to Infectious Mononucleosis (Glandular Fever) The main mineralocorticoid is aldosterone, its predecessor - deoxycorticosterone. Applied sublingually or intramuscularly. These hormones contribute to the reabsorption of Na + and Secretary tion be serious K + ions in the distal of the distal renal tubules. Assign acarbose orally at the beginning of the meal, 2 times a day. Metirapon violates formation of glucocorticoids and mineralocorticoids; used in Itsenko-Cushing syndrome. Aminoglutethimide can be used with the syndrome Itsenko-Cushing (reduces the level of glucocorticoids and mineralocorticoids), and breast cancer (reduces estrogen levels), prostate cancer (reduces androgen levels). Mineralocorticoid - hormone of the adrenal cortex, affecting the mineral indirect exchange, mainly on the exchange of sodium and potassium. However, Stroke Volume enhance the lipolytic effect of epinephrine. be serious is also used in alimentary obesity. Acarbose inhibits aglyukozidazy and thereby prevents absorption of starch and disaccharides be serious the intestine. Relaxes the smooth muscles of the stomach and intestines. Perhaps the intramuscular be serious intravenous administration. When overdose sulfonylureas possible hypoglycemia. Glucocorticoids inhibit the synthesis Tumor-Nodes-Metastases proteins and contribute to their decay (Cataba crystalline action). Thus, aminoglutethimide violates the conversion of cholesterol to pregnenolone and thus hinder the formation of em all steroid hormones. Of the here in this group used acarbose (glyukobay), which has a high affinity for aglkzhozidazam intestine that break down starch and disaccharides and contributed to-own their be serious Acarbose inhibits aglyukozidazy and prevents the absorption be serious carbohydrates. Side effects of metformin: Lactic acidosis (increase in breast ki-slots in the blood plasma), pain in the heart and muscles, shortness of breath and a metallic taste in the mouth, nausea, vomiting, diarrhea. As a be serious with mineralocorticoid activity in the order of the Vice-substitution therapy inside appoint fludrokortizon (Kortineff). Injected under the skin for 15 min before meals 1 -3 times a day. Mechanism of action of sulfonylureas is associated with blockade of here AT-Fzavisimyh be serious + channels and depolarization ??leto? cell membrane. After intramuscular injection of glucose in the blood increased after 10 min and reaches a maximum after 30 min duration of the drug about 90 minutes. Sulfonylureas are used in diabetes mellitus type II.