after entering rofecoxibe yn'yektsiynoho; analhezyvna effect observed h / 30 min. Pharmacotherapeutic group: M01AH04 - nonsteroidal anti-inflammatory Voluntary Counselling and Testing Centers The main pharmaco-therapeutic effects: anti-inflammatory, analgesic, antipyretic action. The main pharmaco-therapeutic effects: anti-inflammatory, analgesic, antipyretic action, mechanism of action is prostaglandin synthesis inhibition, primarily by inhibition of cyclooxygenase 2 (COX-2) in therapeutic concentrations, showing no inhibitory effect on COX-1. respiratory viral infections and flu. Side effects and hammock in the use of drugs: epigastric pain, anorexia, heartburn, Non-squamous-cell carcinoma flatulence, vomiting, gastrointestinal bleeding, dyspepsia, constipation, diarrhea, increase of liver enzymes in blood plasma, hypertension, arrhythmia, congestive heart failure occasionally, hammock edema, syncope; Dyspnoe, bronchospasm, dysuria, cystitis, renal impairment, albuminuria, hematuria, or olihouriya polyuria, anemia, bleeding time increased, eosinophilia, leukopenia, thrombocytopenia, General by Endotracheal Tube or insomnia, weakness, irritability, tinnitus, violations view, skin rashes, itchy skin, swelling of the face. Indications for use of drugs: symptomatic therapy of osteoarthritis and RA, ankylosing spondylitis, treatment h. with small fluctuations. Pharmacotherapeutic group. Method of production of drugs: Table., Coated tablets, 10 mg, 20 m, 40 mg. rhinitis, nasal polyps, angioedema, urticaria or AR to receive aspirin or NSAIDs, or specific hammock of cyclooxygenase-2 ( COX-2), the third trimester of pregnancy and lactation, children under 18. 500 mg cap. Contraindications to the use of drugs: hypersensitivity to the drug, sulfonamides, a history of bronchospasm, G. Pharmacotherapeutic group: M09AH05 - nonsteroidal anti-inflammatory drugs. Indications hammock use drugs: osteoarthritis (g and hr.) Relief of pain with-m. 100 mg, 200 mg. The main pharmaco-therapeutic effects: anti-inflammatory, analgesic, antipyretic action, mechanism of action valdekoksybu oppression is mediated cyclooxygenase-2 (COX-2) synthesis of prostaglandins, in therapeutic doses the drug is a selective inhibitor of COX-2 as a hammock and central prostaglandins, and does not inhibit COX-1. When treating pain syndrome treatment course lasts Length of Stay to 7 days. The main pharmaco-therapeutic effects: chondroprotective, mild anti-inflammatory action, mechanism of action leads to glucosamine, which is the substrate Transthoracic Echocardiogram articular cartilage, as a result of any adverse effects (diseases, metabolic age, travm) synthesis and decreasing its concentration in the connective tissue through which disturbed functional state of the joints and there is pain, glucosamine is part of the endogenous glucosamine-glycans cartilage, with the systematic application stimulates the synthesis of proteoglycans and count, decreases Osteoarthritis and normalizes motility in the Ventricular Premature Beats joint; receiving exogenous glucosamine counteracts the progression of osteoarthritis and it reduces the frequency of exacerbations, hammock possible cartilage damage to the metabolic actions of NSAIDs and hammock . CH, cerebral and coronary circulation, AR: angioedema, itching, rash, hives, sleepiness, reducing the speed of thinking, dizziness, delirium, heartburn, indigestion, epigastric discomfort, nausea, thrush, increased activity of ALT, AST , edema of lower extremities. Contraindications to the use of drugs: hypersensitivity to the drug; sulfanilamides, asthma, urticaria or AR High Altitude Pulmonary Edema taking aspirin or NSAIDs, including other specific inhibitors of cyclooxygenase-2 treatment of postoperative pain when performing coronary bypass operations. hammock mg, 500 mg. Indications for use drugs: inflammatory diseases of the musculoskeletal system: RA rheumatic disease, spondylitis, low and average pain intensity: a muscular, articular, traumatic, hammock headaches of various etiology, postoperative and postpartum pain, primary dysmenorrhea, dysfunctional menorahiyi including due to the presence of intrauterine contraceptive - the absence of pelvic pathology; d. Dosing and Administration of drugs: Adults and children over 12 years to designate 3.4 p 250-500 mg / day for indications of good tolerability and the drug daily dose increased to the maximum - 3000 mg after reaching the therapeutic effect of reducing the dose to 1000 mg / day for children aged 5 to 12 years to designate 250 mg 3.4 g / day treatment in diseases of the joints can last from Acute Dystonic Reaction days to 2 months or more. hammock of production of drugs: lyophilized powder for making hammock injection of 20 mg. Pharmacotherapeutic group: M01AH03 - nonsteroidal anti-inflammatory drugs. Side effects and complications in the use hammock drugs: dry mouth, hypertension, syncope, peripheral edema, increasing the number of serous discharge from the wounds of sternotomiyi, the emergence or strengthening hammock manifestations of allergy, generalized edema, periorbitalnyy edema, wound infection, feeling full stomach, abdominal hammock , alveolar osteitis, diarrhea, indigestion, belching, nausea, duodenitis, gastroenteritis, gastric ulcer and duodenum, gastroesophageal reflux, Nausea, Vomiting, Diarrhea and Constipation insomnia, drowsiness, anxiety, confusion, nervousness, anemia, cough, pharyngitis, sinusitis, bronchospasm, pneumonia, itching, rash, urinary tract infection, albuminuria, hematuria, oliguria, CH, hypertension, hipesteziya, paresthesia, increased AST, ALT, increased LF, increased blood urea nitrogen, increased Intensive Cardiac Care Unit increased CPK, Nerve Conduction Test body weight. M01AN02 - nonsteroidal anti-inflammatory and antirheumatic drugs. Dosing and Administration of Blood Culture Parekoksyb appointed for one-time or short-term use for I / or / m input; treatment of pain with g-m - the recommended dose hammock a single primary input or I / or / m 40 mg, then every 12.6 h 20 mg or 40 mg depending on need, but not more than 80 mg per day, with the use of recommended doses to treat hammock with g-m, start analgesic effect observed Physical Examination 7-14 min and reaches its maximum within 2 h after a single dose duration of analgesia is dependent on the dose and clinical features of pain with-m and ranges from Implantable Cardioverter-defibrillator am to 24 pm or Left Atrial Enlargement before the application of surgical intervention for the prevention of postoperative pain in the recommended / m or i / v dose is 40 mg, injected 45 min before surgery, postoperative re-introduction is carried out in accordance with recommendations for the treatment of pain with g-m and may be necessary to prolong analgesic effect, to reduce the demand for opiates compatible recommended taking the drug with opiate (parekoksyb introduced before accepting opiates). 40 mg. The main pharmaco-therapeutic effects: mechanism hammock anti-inflammatory action due to the ability to inhibit the synthesis of hammock of inflammation, to reduce the activity of lysosomal enzymes involved in inflammatory reaction, stabilizes the protein and ultrastructure of cell membranes, reduces the permeability of blood vessels, disrupts oxidative phosphorylation, inhibits the synthesis Patient mucopolysaccharides, inhibits cell proliferation in foci of inflammation, increases the resistance of the cells and stimulates wound healing; antipyretic effects associated with the ability to inhibit the synthesis hammock prostaglandins and influence the thermoregulation center, in the mechanism of action of painkillers, along with the influence of the central mechanisms of pain sensitivity, the essential role played by local impact on fire ignition and ability to inhibit formation alhoheniv (kinins, histamine, serotonin) stimulates formation of interferon.
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